PT-141
Also known as Bremelanotide · Vyleesi
Melanocortin receptor agonist studied for centrally mediated effects on sexual desire and arousal in men and women.
Mechanism of action
How PT-141 works
Activates melanocortin receptors (primarily MC4R) in the central nervous system, producing pro-sexual effects independent of vascular pathways.
Areas of study
What PT-141 is studied for
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Hypoactive sexual desire disorder (HSDD) in premenopausal women
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Adjunctive support for sexual function in men
Considerations
Important things your physician will discuss
This is general clinical context — not medical advice. Your evaluation determines whether PT-141 is appropriate for you.
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Transient blood-pressure elevation is reported — uncontrolled hypertension is a contraindication
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Nausea is the most common side effect; dosing should be titrated under supervision
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